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What is Hyperpigmentation

Hyperpigmentation is a common skin condition in which some areas of the skin become darker in colour than the surrounding skin.


Hyperpigmentation occurs when an excess of melanin is produced by melanocytes, the pigment cells, which are moved up to the skin’s surface.


Hyperpigmentation can be caused by inflammation, hormonalstress, sun damage, or other skin injuries. People with darker skin tones are more prone to hyperpigmentation, especially with excess sun exposure.

Why Cysteamine


Cysteamine is one of the strongest antioxidants naturally present in the human body, and its action reduces melanin pigment in the skin. 


It helps to remove brown spots, reduces pigmented marks and produces an even and lighter skin complexion.


First & Only

Skin pigment corrector containing Cysteamine as an active biogenic ingredient



Significant efficacy clinically-proven (Ref 2). Set to replace hydroquinone as the new standard for hyperpigmentation concerns (Ref 1)


Clinical studies have shown its significant efficacy (Ref 2), and researchers confirmed the superior benefits of Cysteamine compared to Hydroquinone (Ref 1)


Hydroquinone-free, retinoic acid free, kojic acid free, corticosteroid-free, non-cytotoxic, non-mutagenic, non-carcinogenic, increase production of glutathione naturally.


Hyperpigmentation therapies are a long and difficult process. It is important to keep in mind when treating hyperpigmentation - there are no quick fix. It needs time, patience, and compliance with the daily program over weeks.

Ref 1: Wang Y & Marini L “A review on the efficacy and safety of L-cysteamine as a skin depigmenting agent. AAD 2018, ePoster 7687

Ref 2: Mansouri, P.; Farshi, S.; Hashemi, Z.; Kasraee, B. (July 2015).»Evaluationof the efficacy of cysteamine 5% cream in the treatment of epidermal melasma: a randomized double-blind placebo-controlled trial». The British Journal of Dermatology. 173 (1): 209–21

Contradiction to the use of Cysteamine Cream:

Cysteamine cream should not be used by anyone with a personal or family history of the depigmenting disorder, vitiligo. No study has been performed during pregnancy, breast-feeding and patient under the age of 18 year old, therefore it should not be used by this group of patients.



Effects of Cysteamine on melasma

Melanin pigment correction after

Cysteamine application, measured

by Mexameter (Ref 2)

Intensive Phase

15 minutes daily for up to 12 weeks

Week 0



Week 12

Correction of


Week 6

Initial Improvement

Maintenance Phase


Once optimal result has been achieved,

you may reduce Cysteamine to twice weekly.

The use of high SPF sunblock is highly recommended

year-round for sun damage protection.




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